**Fusion Pharmaceuticals, a member of the AstraZeneca Group,**is a clinical-stage oncology company focused on developing next-generation radioconjugates (RCs) as precision medicines. Fusion connects alpha particle emitting isotopes to various targeting molecules to selectively deliver the alpha emitting payloads to tumors. Fusion’s clinical portfolio includes: FPI-2265 targeting prostate specific membrane antigen (PSMA) for metastatic castration resistant prostate cancer currently in a Phase 2 trial; FPI-1434 targeting insulin-like growth factor 1 receptor currently in a Phase 1 trial; FPI-2059, a small molecule targeting neurotensin receptor 1 (NTSR1), currently in a Phase 1 trial; and FPI-2068, a bispecific IgG-based EGFR-cMET targeted radioconjugate currently in a Phase 1 trial. In addition, Fusion is pursuing combination programs between RCs and DNA Damage Response Inhibitors (DDRis) and immune-oncology agents. Fusion has a fully operational Good Manufacturing Practice (GMP) compliant state-of-the-art radiopharmaceutical manufacturing facility to meet supply demand for Fusion's growing pipeline of RCs.

The Scientist, Radiochemistry role is an onsite, lab position in Hamilton, Ontario.

Responsibilities and job tasks**(including, but not limited to):**

• Effectively execute routine radiolabeling productions for a range of targeting moieties (small molecules to mAbs) and radioisotopes in support of biological studies as a part of the Discovery team
• Contribute to the preparation, purification and characterization of novel radioconjugates including stability assessments
• Assist in the synthesis of radiolabeling precursors as required
• Analyze and interpret data
• Maintain clear and current records of work within a laboratory notebook
• Contribute to the organization and maintenance of all chemistry laboratories including waste streams in collaboration with operations and health physics teams
• Effectively communicate scientific findings, which may come in the form of writing reports and presentations

Qualifications

• B.S. required, M.S. desired with 2-5 years of relevant laboratory experience

• Driven radiochemist with a recognized post-secondary education in radiochemistry, inorganic chemistry, organometallic chemistry or a related discipline

• Experience with bioconjugations and medicinal synthetic chemistry is also desirable

• Experience in performing in vitro assays with radioconjugates is desirable

• Excellent troubleshooting skills in the lab, organizational skills and an understanding of the radiopharmaceutical field

• Experience with analytical HPLC method development and Empower software

• Proven ability to work independently with strong communication skills and attention to detail, including proficiency in the English language

• Demonstrable independent research accomplishments

• Excel at working in a fast-paced, collaborative environment as a member of a multidisciplinary team

• Knowledge of good laboratory practices is an asset

• Demonstrated ability to successfully prioritize tasks and manage timelines

• Experience in the safe handling and analysis of radiometal conjugates is desirable