Research Technician II

Résumé du poste

The Research Technician will develop an intra-cranial mouse model of glioblastoma by performing survival surgeries and injecting patient-derived glioma stem cells. They will also maintain cell cultures, harvest brain tissue, and perform immunofluorescence imaging to analyze tumor infiltration.

Détails du poste

Company Description UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto. UHN’s vision is to build A Healthier World and it’s only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality. www.uhn.ca Job Description Union: Non-Union Number of vacancies: 1 New or Replacement Position: New Site: Princess Margaret Cancer Centre Department: Research Reports to: Senior Scientist Salary Range: $31.02 - $38.78 per hour Hours: 37.5 hours per week Shifts: Day Status: Temporary Full-time (1 year contract) Closing Date: September 30, 2026 Position Summary Princess Margaret Cancer Centre is seeking a dedicated and professional Research Technician to join a multi-disciplinary team researching glioblastoma, an aggressive type of brain cancer. The Diamandis lab is seeking to establish an intra-cranial mouse model of glioblastoma involving the injection of patient-derived glioma stem cells into the brains of living mice. The successful candidate will play a key role in developing this mouse model. Their primary responsibilities will include troubleshooting the stereotaxic setup necessary to immobilize anesthetised mice, identifying the ideal location for tumor cell injection and determining the appropriate number of tumor cells and length of time for a glioblastoma tumor to reproducibly establish within the mice. Given these responsibilities, the successful candidate must be comfortable handling and performing survival surgeries on mice, and ideally will have 2+ years of experience with rodent surgery. This position is fully on-site (no remote component). In your application, please send a resume and a cover letter, as well as the names and contact information of three references. Duties Culture/maintain glioma stem cells and assist with wet lab experiments. Troubleshoot stereotaxic setup necessary to immobilize anesthetised mice. Identify ideal location to inject glioma stem cells into brains of immobilized mice. Determine appropriate number of tumor cells and length of time for a glioblastoma tumor to reproducibly establish within the mice. Harvest brain tissue from mice and perform immunofluorescence and imaging to assess extent of tumor brain infiltration. Assist other lab members with projects involving in vivo glioblastoma mouse model. Qualifications At minimum, Bachelor's degree in Molecular Biology, Cancer Biology, Cell Biology, or a related field required. Minimum of 3 years of relevant wet-lab experience – with at least 2 years of experience with mouse research Ability to follow, optimize, and troubleshoot complex experimental protocols. Strong organizational skills and attention to detail. Ability to maintain clear/accurate experimental records. Excellent communication skills and fluency in English. Ability to work effectively in a collaborative, multidisciplinary research environment. Additional Information Why join UHN? In addition to working alongside some of the most talented and inspiring healthcare professionals in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN. Competitive offer packages Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/) Close access to Transit and UHN shuttle service A flexible work environment Opportunities for development and promotions within a large organization Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.) Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration. All applications must be submitted before the posting close date. UHN uses email to communicate with selected candidates. Please ensure you check your email regularly. At University Health Network (UHN), artificial intelligence technologies may be used to assist in the screening, assessment, and selection of candidates for this position. Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application. UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known. We thank all applicants for their interest, however, only those selected for further consideration will be contacted. Department: Research Compensation: CAD 31.02 - CAD 38.78 - hourly

Ce que vous ferez

The Research Technician will develop an intra-cranial mouse model of glioblastoma by performing survival surgeries and injecting patient-derived glioma stem cells. They will also maintain cell cultures, harvest brain tissue, and perform immunofluorescence imaging to analyze tumor infiltration.

Exigences

Candidates must hold at least a Bachelor's degree in a biological science and possess a minimum of 3 years of wet-lab experience. Specifically, at least 2 years of experience with mouse research and survival surgery is required.

Avantages

• Healthcare of Ontario Pension Plan • Transit access • Shuttle service • Corporate discounts • On-site gyms • Professional development opportunities

Compétences indiquées

• Collaboration · Souhaitée
• Communication Skills · Souhaitée

Autres compétences pertinentes

Relevées dans la description du poste. Confirmez les exigences importantes ci-dessus.

• Mouse handling
• Rodent surgery
• Stereotaxic setup
• Glioma stem cell culture
• Immunofluorescence
• Imaging
• Molecular biology
• Cancer biology
• Cell biology
• Experimental protocol optimization
• Data recording
• Communication skills
• Collaboration
• Cancer Biology
• Laboratory Experience
• Research Reports
• Organizational Skills
• Research
• Artificial Intelligence
• Cell Biology
• Molecular Biology
• Medical Research
• Management
• Cardiology
• Communication
• English Language
• Innovation
• Infectious Diseases
• Oncology
• Multidisciplinary Research
• Rehabilitation
• Physical Medicine And Rehabilitation
• Surgery
• Troubleshooting (Problem Solving)
• Detail Oriented

Domaines d’emploi

• Science & Research
• Healthcare
• Research Technician
• Biology Laboratory Technician
• Medical and Pathology Laboratory Technicians
• Medical and Clinical Laboratory Technicians
• Clinical Laboratory Technologists and Technicians